Cost-Effective Interventions

Interventions are actions taken by or for individuals to reduce the risk, duration, or severity of adverse health conditions. Interventions may be population-based or personal.

DCP2 and GBD present what we know about which health interventions work for a comprehensive range of diseases, injuries, and disabilities in many different contexts. A large share of the disease burden in low- and middle-income countries is attributable to diseases and conditions for which cost-effective interventions are already known and feasible. Selecting the right intervention for a given disease and context matters a great deal. The tools on this page are designed to aid the task.

DCP2 and GBD demonstrate how decision makers could use cost-effectiveness information in combination with information on disease prevalence and avertable illness to determine which interventions should be extended and which ones should be questioned. If developing countries scale up interventions and extend health care services that are cost-effective, the impact on the disease burden could be substantial.

Select Criteria

Disease / Condition Setting Type Objective Target population

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Condition Intervention Intervention type Intervention description Intervention setting Objective Target population Cost effectiveness (US$/DALY) Cost effectiveness estimate (US$) Cost effectiveness range (US$/DALY) Number of DALYs averted (hundreds) Number of deaths averted (hundreds) Quality of cost-effectiveness analysis evidence
Diarrheal disease Breastfeeding promotion Population Promotion of exclusive breastfeeding (recommended for six months) to new mothers, in which no other food or drink, including water, is permitted, except for supplements of vitamins and minerals and necessary medicines Community, Clinic, Local or district hospital personal behavior change Adults, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 930 - -- 0.43 1.33 5
Diarrheal disease Cholera or rotavirus immunization Population Immunization for endemic cholera with live oral vaccine or rotavirus immunization with rhesus-human rotavirus reassortant-tetravalent vaccine (currently under development) in populations at risk of an outbreak Clinic population-oriented medical intervention Infants or children, Mothers and infants 2,712 - 2,478-2,945 0.62 1.98 5
Diarrheal disease Construction and promotion of basic sanitation where facilities are limited Population Construction of low-cost excreta disposal facilities such as household pit latrines, ventilationimproved latrines, or pour-flush toilets, combined with public promotion of sanitation and hygiene Policy level, Community instrument of policy, control of environmental hazards All ages, Adults, Infants or children, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 141 - 11-270 -- -- 1
Diarrheal disease Hand pump, standpost, or house connection where clean water supply is limited Population Installation of hand water pump, standpost, or house connection where clean water supply is limited and associated infrastructure currently do not exist Community control of environmental hazards All ages, Adults, Infants or children, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 159 - -- -- -- 1
Diarrhea Improved quality of care Population Educational interventions to improve quality of care and encourage oral rehydration therapy in hospitals; varies with marginal improvement; low to average prevalence Clinic, Local or district hospital instrument of policy All ages, Adults, Infants or children, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants - 14-6000a per death averted - - - 4
Diarrheal disease Improved water and sanitation at current coverage of amenities and other interventions Population Improved water supply and excreta disposal where established infrastructure currently exists, in urban or rural settings for at least five years Community control of environmental hazards All ages, Adults, Infants or children, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 4,185 - 1,974-6,39 3.52 315.3 5
Diarrheal disease Oral rehydration therapy for package costing $5.50 per episode Personal Case management of acute diarrheal infection with oral rehydration salt solutions, for package costing $5.50 per child per episode Clinic acute management Infants or children, Mothers and infants 1,062 - -- 16.57 58.2 5
Diarrheal disease Water sector regulation with advocacy where clean water supply is limited Population Surveillance of drinking water quality and quality of service by the water supply utility in terms of coverage, quantity, continuity, control of sanitary hazards, and cost, as well as advocacy of lower connection charges Policy level, Community instrument of policy, control of environmental hazards All ages, Adults, Infants or children, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 47 - -- -- -- 1

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