Cost-Effective Interventions

Interventions are actions taken by or for individuals to reduce the risk, duration, or severity of adverse health conditions. Interventions may be population-based or personal.

DCP2 and GBD present what we know about which health interventions work for a comprehensive range of diseases, injuries, and disabilities in many different contexts. A large share of the disease burden in low- and middle-income countries is attributable to diseases and conditions for which cost-effective interventions are already known and feasible. Selecting the right intervention for a given disease and context matters a great deal. The tools on this page are designed to aid the task.

DCP2 and GBD demonstrate how decision makers could use cost-effectiveness information in combination with information on disease prevalence and avertable illness to determine which interventions should be extended and which ones should be questioned. If developing countries scale up interventions and extend health care services that are cost-effective, the impact on the disease burden could be substantial.

Select Criteria

Disease / Condition Setting Type Objective Target population

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Condition Intervention Intervention type Intervention description Intervention setting Objective Target population Cost effectiveness (US$/DALY) Cost effectiveness estimate (US$) Cost effectiveness range (US$/DALY) Number of DALYs averted (hundreds) Number of deaths averted (hundreds) Quality of cost-effectiveness analysis evidence
Hib, and hepatitis B, diphtheria, pertussis, and tetanus Pentavalent vaccine Population Hib vaccination (three or four doses) and hepatitis B (three or four doses) given concurrently with diphtheria-pertussistetanus Clinic population-oriented medical intervention Infants or children, Mothers and infants 296d - -- -- -- 5
Adolescent health and nutrition School health and nutrition programs Population Inclusion of deworming of intestinal worms and schistosomiasis; prompt recognition and treatment of malaria; insecticide-treated bednets; micronutrient supplements; breakfast, snacks, other meals; first-aid kits; referral to youthfriendly clinics; and cou Community, School population-oriented medical intervention Infants or children, Adolescents and adults 37 - -- -- -- 3
Tuberculosis, diphtheria, pertussis, tetanus, polio, measles Traditional Expanded Program on Immunization (EPI) Population Scaling up of EPI; a fixed increment of coverage added for each year 2002-11 to reach 90 percent; coverage increases assumed to result from switching to more effective and intensive implementation strategies rather than additional infrastructure investmen Community population-oriented medical intervention Infants or children, Mothers and infants 7 - -- -- -- 5

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