Cost-Effective Interventions

Interventions are actions taken by or for individuals to reduce the risk, duration, or severity of adverse health conditions. Interventions may be population-based or personal.

DCP2 and GBD present what we know about which health interventions work for a comprehensive range of diseases, injuries, and disabilities in many different contexts. A large share of the disease burden in low- and middle-income countries is attributable to diseases and conditions for which cost-effective interventions are already known and feasible. Selecting the right intervention for a given disease and context matters a great deal. The tools on this page are designed to aid the task.

DCP2 and GBD demonstrate how decision makers could use cost-effectiveness information in combination with information on disease prevalence and avertable illness to determine which interventions should be extended and which ones should be questioned. If developing countries scale up interventions and extend health care services that are cost-effective, the impact on the disease burden could be substantial.

Select Criteria

Disease / Condition Setting Type Objective Target population

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Condition Intervention Intervention type Intervention description Intervention setting Objective Target population Cost effectiveness (US$/DALY) Cost effectiveness estimate (US$) Cost effectiveness range (US$/DALY) Number of DALYs averted (hundreds) Number of deaths averted (hundreds) Quality of cost-effectiveness analysis evidence
Maternal mortality Improved overall quality of care Personal Improvements to quality of prenatal and delivery care; enhanced package including availability of doctor and full range of basic and comprehensive emergency obstetric care (all six essential obstetric functions: administering antibiotics intravenously or Clinic primary prevention, acute management Adults, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 147 (South Asia), 83 (SubSaharan Africa) - 133-160 (South Asia), 82-85 (SubSaharan Africa) 21.90 (South Asia), 53.05 (Sub-Saharan Africa) 56.20 (South Asia), 153.20 (Sub-Saharan Africa) 5 (South Asia), 5 (Sub-Saharan Africa)
Maternal mortality Improved quality of care and coverage Personal Improvements to quality of prenatal and delivery care and increase in the proportion of women receiving needed care; enhanced package including availability of doctor and full range of basic and comprehensive emergency obstetric care (all six essential ob Clinic primary prevention, acute management Mothers and infants 152 (South Asia), 86 (SubSaharan Africa) - 138-167 (South Asia), 85-86 (SubSaharan Africa) 23.51 (South Asia), 56.93 (Sub-Saharan Africa) 60.29 (South Asia), 164.14 (Sub-Saharan Africa) 5 (South Asia), 5 (Sub-Saharan Africa)
Maternal mortality Improved quality of comprehensive emergency obstetric care Personal Increased percentage of women with severe complications receiving comprehensive emergency obstetric care Clinic, Local or district hospital acute management Adults, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 127 (South Asia), 87 (SubSaharan Africa) - -- 13.28 (South Asia), 28.28 (Sub-Saharan Africa) 32.00 (South Asia), 78.00 (Sub-Saharan Africa) 5 (South Asia), 5 (Sub-Saharan Africa)
Maternal mortality Increased primary care coverage Personal Increased percentage of women accessing routine prenatal, intranatal, and postnatal care Clinic, Local or district hospital primary prevention Adults, Women of childbearing age, Pregnant women, Adolescents and adults, Mothers and infants 132 (South Asia), 88 (SubSaharan Africa) - -- 13.09 (South Asia), 27.88 (Sub-Saharan Africa) 32.00 (South Asia), 77.00 (Sub-Saharan Africa) 5 (South Asia), 5 (Sub-Saharan Africa)
Down syndrome Prenatal screening with option of pregnancy termination Population Prenatal genetic screening program, incorporating maternal serum triple screening of all pregnant women, for trisomy of chromosome 21, to allow parents to determine whether to continue with an affected pregnancy Clinic, Local or district hospital population-oriented medical intervention Women of childbearing age, Pregnant women, Adolescents and adults 15 - -- -- -- 5

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