Cost-Effectiveness of Selected Breast Cancer Treatments for a Hypothetical Cohort of 45-Year-Old Premenopausal Women with Early-Stage Breast Cancer, United States (cost in 2000 US$/quality-adjusted life year)| Treatment | Node-negative, estrogen receptor-positive | Node-negative, estrogen receptor-negative | Node-positive, estrogen receptor-positive | Node-positive, estrogen receptor-negative |
| Tamoxifen | 17,400 | 326,800 | 6,600 | 88,300 |
| Chemotherapy | 17,400 | 7,600 | 14,000 | 7,500 |
| Tamoxifen and chemotherapy | 50,400 | 131,600 | 22,600 | 123,200 |
Source: T. Smith and Hillner 1993.