44. Prevention of Chronic Disease by Means of Diet and Lifestyle Changes

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Research and Development Priorities

A number of research and development priorities have been identified:

  • Conduct randomized trials of the use of folic acid and alpha-linolenic acid to prevent CAD in developing countries. These interventions cost little, and the potential benefits are large and rapid.

  • Develop prospective cohort studies of dietary and lifestyle factors in developing and transition countries to refine the understanding of risk factors in those contexts. To date, almost all such studies have taken place in Europe and North America.

  • Develop surveillance systems for chronic diseases and for major risk factors, such as obesity, in developing countries.

  • Develop additional multifaceted, community-based demonstration programs in developing countries to document the feasibility of lifestyle changes and to learn more about effective strategies.

  • Conduct detailed cost-effectiveness analyses of various prevention strategies to modify dietary and lifestyle factors.